UNIVERSITY OF MICHIGAN – DEPARTMENT OF PHARMACY SERVICES

 

ANNUAL REPORT FY2006

 


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RESEARCH AND EDUCATION

 

Part of the mission of the Department of Pharmacy Sciences is to share knowledge with our peers and one way that this is accomplished is by conducting research and publishing these results in peer reviewed journals.  We maintain our reputation of excellence by showing leadership in scholarly activity.

 

Research

Text Box: Bruce Mueller, Pharm.D.
Professor and Department Chair
College of Pharmacy

The Department's research covers a wide range of inpatient and outpatient drug and disease state management, pharmacokinetics, and pharmacogenomics.  In addition to conducting research itself, we mentor future researchers through our work with residents, pharmacy students and fellows.

 

Pharmacy Residency Class 2005-2006

Specialty

Pharmacy Practice

Greg Eschenauer

(Infectious Diseases)

Aline Saad

(Heme/Onc)

Rima Mohammad

(Critical Care)

Regine Caruthers

(Pediatrics)

Seth Kuiper

(Informatics and Technology)

Dina Mohammad

Ian Hollis

Yaman Kaakeh

 

Pharmacy Residency Class 2006-2007

Specialty

Pharmacy Practice

Dorothy Surowiec

(Infectious Diseases)

Peter Schlickman

(Heme/Onc)

P. Neil L. Edillo

(Informatics and Technology)

Dina Mohammad

(Critical Care)

Jennifer L. Ludwig:

James T. Miller

Kristen T. Reaume

Valerie A. Sanluis

Shawna L. Van De Koppel

 

Additionally, there were approximately 120 student investigations projects last year within the College of Pharmacy.

 

Grants

 

The Department of Clinical Sciences’ Faculty have contributed a total of $568,892 through their grantsmanship efforts in fiscal year 2006. 

 


Funded Fiscal Year, 2006

 

INVESTIGATOR

PI

SPONSOR

TITLE

DIRECT

INDIRECT

TOTAL AWARD

CURRENT PERIOD END

Alaniz

Alaniz

Amgen

A Multicenter, Retrospective, Observational Study to Evaluate Erythropoietic Stimulating Protein (ESP) Use and Clinical Outcomes in Hospitalized Patients (ASSESS)

$23,965

$5,991

$29,956

8/23/2008

Bleske

Bleske

NIH

Mechanisms of Hawthorn's Action in Heart Failure

$125,000

$52,728

$177,728

7/31/2006

DePestel

DePestel

WESTAT

CUBICIN Outcomes Registry and Experience (CORE) for the Treatment of Serious Gram-Positive Infections

$10,811

$1,189

$12,000

12/31/2005

DePestel

DePestel

Cubist

CUBICIN Outcomes Registry and Experience (COREsm) Sub-study for Patients Reported with Osteomyelitis

$1,622

$178

$1,800

10/31/2006

DePestel

Mueller

Merck

Invanz™ Clearance in Continuous Renal Replacement Therapy (CRRT) An In-Vitro Investigation

$43,666

$8,733

$52,399

10/31/2006

Mueller

Mueller

Theravance

Pharmacokinetics of Telavancin During Continuous Renal Replacement Therapy (CRRT):  An In-vitro Investigation

$35,132

$20,377

$55,509

6/30/2006

Mueller

Mueller

Merck

InvanzClearnace in Continuous Renal Replacement Therapy (CRRT) An In-Vitro Investigation

$43,666

$8,733

$52,399

10/31/2006

Mueller

Mueller

Amgen

Pharmacotherapy and Renal Disease

$4,505

$495

$5,000

8/31/2006

Mueller

Mueller

Cubist

Pharmacotherapy and Renal Disease

$4,505

$495

$5,000

8/31/2006

Streetman, Dan

Streetman, Dan

NIH

P-glycoprotein and Steroid-Resistant Nephrotic Syndrome

$150,000

$79,500

$229,500

8/31/2006

Welage

Med School

NIH

K30 Drug Development Grant

$0

$0

$0

5/31/2007

Welage

Streetman, Dan

NIH

P-glycoprotein and Steroid-Resistant Nephrotic Syndrome

$150,000

$79,500

$229,500

8/31/2006

TOTAL

 

 

 

$399,206

$169,686

$568,892

 

 


 

Publications from the Department of Clinical Sciences

 

Book Chapters

 

Berardi RR, Montgomery P. Pancreatitis, in DiPiro JT, Talbert RL, Yee GC et al (eds): Pharmacotherapy: A Pathophysiologic Approach. McGraw-Hill, New York, 6th edition, 2005.

Berardi RR, Welage LS. Peptic Ulcer Disease, in DiPiro JT, Talbert RL, Yee GC et al (eds): Pharmacotherapy: A Pathophysiologic Approach.
McGraw-Hill, New York, 6th edition, 2005.

Chan JL, Berardi RR. Anorectal Disorders, in Handbook of Nonprescription Drugs, American Pharmaceutical Association, 15th Edition, 2006.

Weber A, Berardi RR. Heartburn and Dyspepsia, in Handbook of Nonprescription Drugs, American Pharmaceutical Association, 15th Edition, 2006.

 

Btaiche IF, Marik PE, Ochoa JB, Martindale RG, Salon JE. Nutrition in critical illness, including immunonutrition. In: Merritt R, eds. A.S.P.E.N. Nutrition Support Practice Manual, 2nd ed. Silver Spring, MD: The American Society for Parenteral and Enteral Nutrition; 2005:263-70.

Teitelbaum DH, Btaiche IF, Islan S.  Complications of Nutrition Support:  In:  Mulholland M, Doherty G, eds.  Complication in Surgery.  Philadelphia, PA: Lippincott, Williams & Wilkins; 2005:195-211.

 

Btaiche IF. Chronic Complications associated with Parenteral Nutrition. In: Schumock GT, Dunsworth TS, Brundage DM, et al., eds. Pharmacotherapy Self-Assessment Program (PSAP-V), 5th ed. Kansas City, MO: The American College of Clinical Pharmacy; 2005:163-80.

 

Kraft MD and Btaiche IF. Parenteral Nutrition. In: Malone P, et al., eds. Pharmacotherapy Essentials, 1st ed. 2006 (in press).

Kraft MD.  Parenteral Nutrition. In: Schwinghammer TL, DiPiro JT, Talbert RL, et al., eds. Pharmacotherapy Casebook: A Patient-Focused Approach, 6th ed. New York: McGraw-Hill; 2005. p. 391 – 393.

 

Mueller BA.  Acute Renal Failure in DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM (eds): Pharmacotherapy: A Pathophysiologic Approach, 6th Ed. McGraw-Hill, New York, 2005.

Mueller BA.  Chapter 73: Acute Renal Failure in Wells BG, DiPiro JT, Schwinghammer TL,
Hamilton CW. Pharmacotherapy Handbook. 6th Edition. McGraw-Hill, New York, 2005.

 

Shimp LA.  Disorders Related to Menstruation  (Chapter 9) APhA Handbook of Nonprescription Drugs (15th edition).  American Pharmacists Association, Washington DC 2006

 

Stack NM, Shimp, LA.  Vaginal and Vulvovaginal Disorders (Chapter8) APhA Handbook of Nonprescription Drugs (15th edition).  American Pharmacists Association, Washington DC 2006

 

Stevenson JG (ed). Innovations in medication safety. A compilation of medication safety articles from the Journal of Quality and Patient Safety, Oakbrook Terrace, IL, Joint Commission Resources; 2006.

Stevenson JG, McCreadie SR, Chaffee B. Informatics, In: Brown T (ed), Handbook of Institutional Pharmacy Practice, 4th Edition.
Bethesda, MD: American Society of Health-System Pharmacists; 2006:353-363.

 

Streetman DS.  Review of Human Drug Metabolism: An Introduction. Ann Pharmacother 2006. [Book Review]

 

Stumpf JL, Townsend KA.  Other Anemias, In: Helms R, Quan D, eds. Textbook of Therapeutics: Drug and Disease Management, 8th ed. Baltimore: Lippincott Williams & Wilkins, 2006. Includes online review questions.

Stumpf JL.  Anemia, In:
Salkind NJ, ed. Encyclopedia of Human Development. Thousand Oaks, CA: Sage Publications, 2006.

 

Walker PC.  Diarrhea. In The Handbook of Non-Prescription Drugs. 15th Edition. American Pharmacists Association, Washington, D.C. 2006.

Roth BE, Greenwald BJ,
Maurer VA, Walker PC.  Diarrhea Care: The Healthcare Professional Perspective. Dialogues: New Perspectives in the Treatment of Diarrhea. 2006; 1(1):11. In press. (An editorial published as part of a CME newsletter sponsored by the Office of Continuing Medical Education at the David Geffen School of Medicine at UCLA and the American Pharmacists Association. I served on the editorial board for the publication.

 

Books Edited

 

Berardi RR.  Editor-in-Chief, APhA Handbook of Nonprescription Drugs, 15th Edition, 2006. 2. Gastroenterology Section Editor, APhA Handbook of Nonprescription Drugs,15th Edition, 2006.

 

Btaiche IF.  Adult Nutrition Support Core Curriculum, 2nd Edition The American Society for Parenteral and Enteral Nutrition Silver Spring, MD Pharmacology and the Nursing Process, 4th edition Elsevier, Inc., St. Louis, MO Perianesthesia Nursing: A Critical Care Approach, 5th edition. Elsevier, Inc., St. Louis, MO

 

 

Regal RR.  March- September 2006 Editor/Monograph reviewer, Omnicare Geriatric Pharmaceutical Care Guidelines, 2007 edition. August-September 2005 Editor/Monograph reviewer, Mosby’s Nursing Pharmacology Monographs,2006. Multiple sections.

 

Remington TL.  Headache. In: Handbook of Nonprescription Drugs, 15th Edition. Berardi R, Editor in Chief. American Pharmaceutical Association. April 2006.

Remington TL.  Pharmaceutical Care Spotlight – MTMS and professionalism. MSHP Monitor September 2005.

 

Remington TL.  Pain and Fever Disorders. Handbook of Nonprescription Drugs, 15th Edition. Berardi R, Editor in Chief. American Pharmaceutical Association. April 2006.

 

Sweet BV.  Editorial review board and contributing reviewer, Off-label Drug Facts, J.B. Lippincott Co., St. Louis, Missouri Editorial review panel and contributing reviewer, Drug Facts and Comparisons Pocket Version, J.B. Lippincott Co., St. Louis, Missouri.

 

Sweet BV.  Editorial review board and contributing reviewer, Off-label Drug Facts, J.B. Lippincott Co., St. Louis, Missouri. Reviewed and edited over 40 monographs for this book.

Sweet BV.  Editorial review panel and contributing reviewer, Drug Facts and Comparisons Pocket Version, J.B. Lippincott Co., St. Louis, Missouri. Reviewed and edited over 80 monographs for this book.

 

Wagner DS.  Handbook of Non-Prescription Drugs, 15th Edition, Pregnancy Risk Categories for Non-Prescription. Drugs & Nutritional Supplements. Wagner DS. 2005

 

Peer-Reviewed Journal Articles

Overholser BR, Kays MB, Lagvankar S, Goldman M, Mueller BA, Sowinski KM. Pharmacokinetics of Intravenously Administered Levofloxacin in Men and Women. Pharmacotherapy 2005;25:1310-8.

Anchal S, Kline-Rogers EM, Eagle KA, Fang J, Armstrong DF, Rangarajan K, Otten RF, Stafkey-Mailey DR, Taylor SD, Erickson SR.  Adherence to Medications by Patients After Acute Coronary Syndromes.  Published Online, 4 Oct 2005, www.theannals.com, DOI 10.1345/aph.1G249.

 

Devlin JW, Welage LS, Olsen KM.  Proton Pump Inhibitor Formulary Considerations in the Acutely Ill Part 2:  Clinical Efficacy, Safety, and Economics (CE) (November).  Ann Pharmacother published 4 October 2005, 10.1345/aph.1G176.

 

Cober MP, Johnson CJ.  Otitis Media: Review of the 2004 Treatment Guidelines.  Ann Pharmacother 2005;39:1879-1887. DOI 10.1345/aph.1G190.

 

Johnson CE.  Stability of Pantoprazole in 0.9% Sodium Chloride Injection in Polypropylene Syringes.  Am J Health-Syst Pharm. 2005;62:2410-2.

 

Nau DP, Ellis JJ, Kline-Rogers EM, Mallya U, Eagle KA, Erickson SR.  Gender and perceived severity of cardiac disease:  Evidence that women are “tougher”.  Am J Med (2005) 118, 1256-1261.

 

Bhatt-Mehta V and Annich G.  Sedative clearance during extracorporeal membrane oxygenation.  Perfusion 2005; 20: 309-315.

 

Eschenauer G and Sweet BV.  Pharmacology and Therapeutic Uses of Theanine.  Am J Health Syst Pharm 2006;63 26-30.

 

Pham C QD, Efros CB, Berardi RR.  Cyclosporine for Severe Ulcerative Colitis.  Ann Pharmacother published 20 December 2005, 10.1345/aph.1G374.

 

Walker PC, Alrawi A, Mitchell JF, Regal RE, Khanderia U.  Medication use as a risk factor for falls among hospitalized elderly patients.  Am J Health-Syst Pharm 2005;62:2495-9.

 

Johnson CE, VandeKoppel S, Myers E.  Stability of anhydrous theophylline in extemporaneously prepared alcohol-free oral suspensions.  Am J Health Syst Pharm 2005;62 2518-2520.

 

Kraft, MD, Btaiche IF, Sacks GS.  Review of the refeeding syndrome.  Invited Review.  Nutr Clin Prac, 2005;20:625–633.

 

Wagner DS, Golembiewski J.  Meds on the Move:  From Cupboard to Machine. Journal of PeriAnesthesia Nursing, Vol 20, No 6, Dec. 2005: pp 444-6

 

Sharabash HM, Remington TL, Mar P, Winston R, Walker PC.  Retrospective Review of Metformin in Inpatients and Outpatients at the University of Michigan.  Diabetes Care 200:29(1):170-171.

 

Park JM, Lake KD, Arenas JD, Fontana RJ.  Efficacy and Safety in Low-Dose Valganciclovir in the Prevention of Cytomegalovirus Disease in Adult Liver Transplant Recipients.  Liver Transpl 2006;12:112-116.

 

Btaiche IF, Marik PE, Ochoa JB, Martindale RG, Salon JE.  Nutrition in critical illness, including immunonutrition.  In: Merritt R, eds. A.S.P.E.N. Nutrition Support Practice Manual, 2nd ed. Silver Spring, MD: The American Society for Parenteral and Enteral Nutrition; 2005: 263-70.

 

Btaiche I, Marik PE, Ochoa J, Martindale R, Salon JE.  Nutrition in Critical Illness Including Immunonutrition.  A.S.P.E.N Nutrition Support Practice Manual, 2nd Ed. 2005;263-270.

 

De Smet BD, Erickson SR. Kirking DM.  Self-Reported Adherence in Patients with Asthma.  Ann Pharmacother 2006;40-:414-20.

 

Lin SW, Carver PL, DePestel DD.  Dalbavancin:  A New Option for the Treatment of Gram-Positive Infections.  Ann Pharmacother 2006;40:449-60.

 

Stumpf JL.  Anemia.  Encyclopedia of Human Development, Vol.1.  SAGE Publications, 2006.

 

Pham CQD, Sadowski-Hayes LM, Regal RE.  Prevalent Prescribing of Proton Pump Inhibitors: Prudent or Pernicious?  P&T 2006:31(3),158-167.

 

Nguyen LN, Guthrie SK.  Risperidone Treatment of Bipolar Mania..  Ann Pharmacother published 28 March 2006, 10.1345/aph.1G378.  http://www.theannals.com/cgi/content/abstract/aph.1G378v1?etoc

 

Stevenson JG, Varner DL.  Current issues impacting hospital pharmacy directors.   Hosp Pharm 2006; 41:S11-S15.

 

DeSmet BD, Fendrick AM, Stevenson JG, Bernstein SJ.   Over and under utilization of cox-2 selective inhibitors by primary care physicians and specialists: the tortoise and the hare revisited.  J Gen Intern Med 2006: 21:694-697.

 

Phan H, Pasko DA, Mitchell JF, Shoemaker DS, Glenn DK, Stevenson JG.  Beyond the human eye: using the ValiMed system to validate high-risk intravenous medications.  Pharmacy Purchasing and Products 2005; 2(6):31.

 

Cousins DD, Hermes-DeSantis ER, Stevenson JG.  Expert Opinions in Pharmaceutical Care:  Impact of Combined Drug Delivery Systems.  Continuing Education Monograph Sponsored by the Annenberg Center for Health Sciences at Eisenhower and Akita Consulting.   July 2005. 

 

Stumpf JL, Shehab N, Patel AC.   Safety of Angiotensin-Converting Enzyme Inhibitors in Patients with Insect Venom Allergies.  Ann Pharmacother published 28 March 2006, 10.1345/aph.1G295.  http://www.theannals.com/cgi/content/abstract/aph.1G295v1?etoc

 

Stumpf JL, Lin Shu-Wen.  Effect of Glucosamine on Glucose Control.  Ann Pharmacother published 28 March 2006, 10.1345/aph.1E658.  http://www.theannals.com/cgi/content/abstract/aph.1E658v1?etoc

 

Nguyen V, Sweet BV, Macek T.  Defining the Phases of Clinical Trials.  Am J. Health-Syst Pharm 2006:63, 710-11.

 

Calhoun DA, Murthy SN, Byrant BG, Leudtke SA, Bhatt-Mehta V.  Recent Advances in Neonatal Pharmacotherapy.  Ann Pharmacother 2006;40:710-719. DOI 10.1345/aph.1G212.  http://www.theannals.com/cgi/content/abstract/40/4/710?etoc

 

Awards and Highlights

 

ACCP member Dr. Rosemary L. Berardi, Pharm.D., FCCP, FASHP was selected by the College's Awards Committee to receive the association's prestigious 2005 Education Award. The award was presented in San Francisco on Sunday, October 23, during the Opening General Session of the College's Annual Meeting.

 

Dr. Imad Btaiche has become a member of the Editorial Board of "Nutrition in Clinical Practice", a scientific publication of the American Society for Parenteral and Enteral Nutrition.

 

Dr. Regine Caruthers was hired by the UM Pharmacy Department as a clinical pharmacist

 

Dr. Hae Mi Choe is the recipient of the College of Pharmacy's 2006 Teaching Excellence Award.

 

Dr. Daryl DePestel is the American College of Clinical Pharmacy's new Chair Elect of the ID-PRN for 2005-2006.

 

Dr. Vicki Ellingrod joins the UM College of Pharmacy Department of Clinical Sciences from the University of Iowa.  She is joining the College's Clinical Pharmacogenomics Laboratory.  

 

Dr. Cary Johnson has been named as a Fellow of the American Society of Health-System Pharmacists.

 

The Executive Committee and Board of Regents endorsed the promotion of Dr. Ujjaini Khanderia to Clinical Associate Professor without tenure effective September 1, 2006.

 

Dr. Jace Nielsen has successfully completed a two-year fellowship in critical care under the mentorship of Dr. Lynda Welage.

 

Dr. Nadine Shehab left the institution on August 2006 to accept a Fellowship with the Centers for Disease Control in Atlanta, Georgia.

 

Dr. Aline Saad was hired by the UM Pharmacy Department as a clinical pharmacist (oncology)

 

Dr. Petrea Cober was hired by the UM Pharmacy Department as a clinical pharmacist (pediatrics)

 

Dr. Michael Dorsch was hired by the UM Pharmacy Department as a clinical pharmacist (cardiology)

 

Dr. Linda Stuckey was hired by the UM Pharmacy Department as a clinical pharmacist (transplant)

 

Dr. Denise Markstrom was hired by the UM Pharmacy Department as a clinical pharmacist (hematology oncology)

 

Dr. Jerod Nagel was hired by the UM Pharmacy Department as a clinical pharmacist (infectious disease)

 

Dr. Melissa Pleva was hired by the UM Pharmacy Department as a clinical pharmacist (critical care)

 

Dr. Helen Tamer has been appointed as a regular member of and Vice-Chair to Board CI as an affiliated non-physician scientist for IRBMED for the term of April 15, 2006 through March 31, 2009.  Congratulations Helen!

 

Dr. Mei Tang accepted a critical care fellowship under the mentorship of Dr. Lynda Welage.

 

Dr. Trisha Wells accepted a Clinical Assistant Professor position with the College of Pharmacy.  Her area of clinical practice is at the Brighton Health Clinic.

 

Department of Clinical Sciences’ Faculty were invited to present this past year a total of 34 international or national research presentations, a total of 77 invited international or national presentations, a total of 35 invited state presentations and a total of 41 invited local presentations.